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Wednesday, May 12, 2010

Topol vs Gurbel: experts split on routine genotyping for DAPT

Routine genotyping to guide dual-antiplatelet therapy (DAPT) seems like a great idea. After all, argue Damani and Topol in a Viewpoint in JACC, the arguments are overwhelming, and the consequences of not rushing to adopt the new technique are dire. They write that loss-of-function and gain-of-function variants of CYP2c19 are extremely common, and are "the root [...]


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